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Immunosuppressive medications help prevent organ rejection following transplantation, yet some patients still experience rejection despite receiving adequate treatment.

Dialysis is a lifesaving medical treatment for people whose kidneys can no longer efficiently filter waste, toxins and excess fluids from the blood.

A human kidney is built once, before birth, and the rules guiding its construction have been largely inferred from animal models. Researchers at Penn Medicine have now read those rules directly in human tissue. They found that developing cells are steered by soluble signals relea